Interestingly, many prominent people have this unusual ailment, which you may not have recognized right away. Continue reading to see some of our favorite celebrities with this eye pigmentation.
#1 Jessica Cauffiel
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Cauffiel has one green eye and one green and brown eye, and she is well recognized for her part in Legally Blonde.#2 Tim McIlrath
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McIlrath's eyes are remarkably different, with one blue and the other brown.#3 David Bowie
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It's widely assumed that Bowie had two different colored eyes. In fact, he had a separate illness termed anisocoria, which was triggered by a childhood accident. His pupils were varied sizes, giving the impression that his eyes were distinct colors.#4 Dan Akroyd
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Akroyd possesses complete heterochromia, with one green and one brown eye.#5 Bill Pullman
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Bill has a more modest type of heterochromia known as sectoral heterochromia, which causes one of his eyes to seem darker due to a brown portion of the iris.#6 Alice Eve
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Alice's eyes stand out; her left is blue, while her right is green. During an interview, she revealed to Conan O'Brien that she had been seeing her partner for 9 months before he noticed.#7 Josh Henderson
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The attractive actor has two distinct eye hues. However, because they are both in the lighter range, you may not realize that one is a medium blue and the other is a rich green right away.#8 Elizabeth Berkley
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The actress is known for more than just her amazing hair and hilarious one-liners. She also has strikingly different eyes, one half-brown and half-green and the other entirely green.#9 Max Scherzer
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This Washington Nationals pitcher has one of the most severe forms of heterochromia, with one eye very light and the other very dark.#10 Jane Seymour
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Did you notice one of her eyes is brown and the other is green? Don't worry, we were also distracted by her gorgeous hair (and terrific acting).#11 Kate Bosworth
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Bosworth's eyes are one of the most well-known examples of heterochromia in Hollywood, with one being blue and the other being a much deeper hazel.#12 Dominic Sherwood
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The actor wasn't always fond of his half-blue, half-brown left eye. In April, he tweeted to a boy who had been ridiculed because of his eye issue, "Your eyes are beyond lovely," he wrote. "It took a long time for me to realize that about my own."#13 Simon Pegg
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Pegg's eyes are mostly blue-grey, but the right one has a distinct brown fleck, making this hilarious man stand out.#14 Christopher Walken
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Walken's eyes are blue with green inner rings, and they are as striking as his acting style.#15 Demi Moore
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You might not have noticed, but Moore has two different colored eyes: hazel and green.#16 Virginia Madsen
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Madsen, a talented actress and '80s star best known for her part in Sideways, has one green eye and one with brown specks.#17 Wentworth Miller
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Miller has one green and one blue eye, which gives him a lovely and perceptive stare.#18 Marshall Lancaster
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Lancaster is most recognized for his work in British television shows. He has one blue eye and one hazel with gold flecks.#19 Ralph Fiennes
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Fiennes has blue eyes with gold and brown flecks, a condition known as partial heterochromia.#20 Colleen Moore
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Moore was a silent film actor who transitioned to talkies and was recognized for having one blue and one brown eye. Her heterochromia can be seen in her black-and-white portraits from that time period.#21 Venus the Cat
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What could earn a cat over 2 million Instagram followers? Her stunning coloring has made her an internet star in addition to being adorable.#22 Benedict Cumberbatch
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Cumberbatch's captivating eyes are a mix of blue, green, and gold. Depending on the lighting, they may appear blue or green overall.#23 Olivia Wilde
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Wilde's irises' inner rings are a different color than the outer rings, giving her blue-green eyes an unusual appearance.#24 Tim Roth
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Roth's heterochromia is particularly dramatic, with dark brown inner rings and green-blue exterior rings.